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Gene: Kdm3a (lysine (K)-specific demethylase 3A) Mus musculus
Symbol: Kdm3a
Name: lysine (K)-specific demethylase 3A
Description: Exhibits DNA-binding transcription factor activity and RNA polymerase II core promoter sequence-specific DNA binding activity. Involved in several processes, including cellular response to leukemia inhibitory factor; histone modification; and positive regulation of cold-induced thermogenesis. Localizes to cytoplasm and nucleus. Is expressed in pituitary gland. Used to study obesity. Human ortholog(s) of this gene implicated in cervical cancer and colon cancer. Orthologous to human KDM3A (lysine demethylase 3A); PARTICIPATES IN histone modification pathway; INTERACTS WITH 2,3',4,4',5-Pentachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1700105C21Rik; [histone H3]-dimethyl-L-lysine(9) demethylase 3A; C230043E16Rik; JHDM2a; jmjC domain-containing histone demethylation protein 2A; Jmjd1; Jmjd1a; jumonji domain containing 1A; jumonji domain-containing protein 1A; KDM2A; lysine-specific demethylase 3A; mKIAA0742; testis specific gene A; TGSA; Tsga
Homo sapiens (human) : KDM3A (lysine demethylase 3A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Kdm3a (lysine demethylase 3A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kdm3a (lysine demethylase 3A)
Pan paniscus (bonobo/pygmy chimpanzee) : KDM3A (lysine demethylase 3A)
Canis lupus familiaris (dog) : KDM3A (lysine demethylase 3A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kdm3a (lysine demethylase 3A)
Sus scrofa (pig) : KDM3A (lysine demethylase 3A)
Chlorocebus sabaeus (African green monkey) : KDM3A (lysine demethylase 3A)
Heterocephalus glaber (naked mole-rat) : Kdm3a (lysine demethylase 3A)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl671,588,972 - 71,632,990 (-)EnsemblGRCm38mm10GRCm38
GRCm38671,588,970 - 71,632,990 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37671,538,966 - 71,582,899 (-)NCBIGRCm37mm9NCBIm37
MGSCv36671,518,550 - 71,562,078 (-)NCBImm8
Celera673,672,792 - 73,716,729 (-)NCBICelera
Cytogenetic Map6C1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Kdm3a
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 737255
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.