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Gene: GUSB (glucuronidase beta) Homo sapiens
Symbol: GUSB
Name: glucuronidase beta
Description: Exhibits protein domain specific binding activity and signaling receptor binding activity. Predicted to be involved in carbohydrate metabolic process; hyaluronan catabolic process; and neutrophil degranulation. Localizes to the extracellular space and intracellular membrane-bounded organelle. Implicated in Sly syndrome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: beta-D-glucuronidase; beta-G1; beta-glucuronidase; BG; FLJ39445; glucuronidase, beta; MPS7
Mus musculus (house mouse) : Gusb (glucuronidase, beta)  MGI  Alliance
Rattus norvegicus (Norway rat) : Gusb (glucuronidase, beta)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gusb (glucuronidase beta)
Pan paniscus (bonobo/pygmy chimpanzee) : GUSB (glucuronidase beta)
Canis lupus familiaris (dog) : GUSB (glucuronidase beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gusb (glucuronidase beta)
Sus scrofa (pig) : GUSB (glucuronidase beta)
more info ...
Related Pseudogenes: GUSBP1   GUSBP10   GUSBP12   GUSBP13   GUSBP14   GUSBP15   GUSBP16   GUSBP2   GUSBP3   GUSBP4   GUSBP5   GUSBP6   GUSBP7   GUSBP8   GUSBP9  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38765,960,684 - 65,982,230 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37765,425,671 - 65,447,301 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36765,063,106 - 65,084,681 (-)NCBINCBI36hg18NCBI36
Build 34764,869,824 - 64,891,346NCBI
Celera766,666,375 - 66,688,005 (+)NCBI
Cytogenetic Map7q11.21NCBI
HuRef761,613,080 - 61,634,635 (-)NCBIHuRef
CHM1_1765,520,933 - 65,542,533 (-)NCBICHM1_1
CRA_TCAGchr7v2764,763,190 - 64,784,820 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on GUSB
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 737258
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.