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Gene: HNRNPL (heterogeneous nuclear ribonucleoprotein L) Homo sapiens
Symbol: HNRNPL
Name: heterogeneous nuclear ribonucleoprotein L
Description: Exhibits pre-mRNA intronic binding activity and transcription regulatory region sequence-specific DNA binding activity. Involved in regulation of alternative mRNA splicing, via spliceosome. Localizes to nucleoplasm; ribonucleoprotein complex; and ribonucleoprotein granule. Implicated in hepatocellular carcinoma; lung cancer; and systemic scleroderma. Biomarker of Sertoli cell-only syndrome and brain cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FLJ35509; hnRNP L; hnRNP-L; HNRPL; P/OKcl.14
Mus musculus (house mouse) : Hnrnpl (heterogeneous nuclear ribonucleoprotein L)  MGI  Alliance
Rattus norvegicus (Norway rat) : Hnrnpl (heterogeneous nuclear ribonucleoprotein L)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hnrnpl (heterogeneous nuclear ribonucleoprotein L)
Pan paniscus (bonobo/pygmy chimpanzee) : HNRNPL (heterogeneous nuclear ribonucleoprotein L)
Canis lupus familiaris (dog) : HNRNPL (heterogeneous nuclear ribonucleoprotein L)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hnrnpl (heterogeneous nuclear ribonucleoprotein L)
Sus scrofa (pig) : HNRNPL (heterogeneous nuclear ribonucleoprotein L)
Chlorocebus sabaeus (African green monkey) : HNRNPL (heterogeneous nuclear ribonucleoprotein L)
Heterocephalus glaber (naked mole-rat) : Hnrnpl (heterogeneous nuclear ribonucleoprotein L)
more info ...
Related Pseudogenes: HNRNPLP1   HNRNPLP2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1938,836,388 - 38,852,347 (-)EnsemblGRCh38hg38GRCh38
GRCh381938,836,370 - 38,852,347 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371939,327,028 - 39,342,979 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361944,018,868 - 44,034,819 (-)NCBINCBI36hg18NCBI36
Build 341944,018,868 - 44,032,457NCBI
Celera1936,129,470 - 36,145,420 (-)NCBI
Cytogenetic Map19q13.2NCBI
HuRef1935,773,794 - 35,789,557 (-)NCBIHuRef
CHM1_11939,327,480 - 39,343,450 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on HNRNPL
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 737263
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.