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Gene: PLAA (phospholipase A2 activating protein) Homo sapiens
Symbol: PLAA
Name: phospholipase A2 activating protein
Description: Predicted to have ubiquitin binding activity. Involved in cellular response to lipopolysaccharide; macroautophagy; and positive regulation of phospholipase A2 activity. Localizes to the cytoplasm; extracellular exosome; and nucleus; PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH (+)-catechin; 17beta-estradiol; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DOA1; DOA1 homolog; FLJ11281; FLJ12699; NDMSBA; phospholipase A-2-activating protein; phospholipase a2, activating protein; PLA2P; PLAP
Mus musculus (house mouse) : Plaa (phospholipase A2, activating protein)  MGI  Alliance
Rattus norvegicus (Norway rat) : Plaa (phospholipase A2, activating protein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Plaa (phospholipase A2 activating protein)
Pan paniscus (bonobo/pygmy chimpanzee) : PLAA (phospholipase A2 activating protein)
Canis lupus familiaris (dog) : PLAA (phospholipase A2 activating protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Plaa (phospholipase A2 activating protein)
Sus scrofa (pig) : PLAA (phospholipase A2 activating protein)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38926,903,372 - 26,947,473 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37926,903,368 - 26,947,468 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36926,894,518 - 26,937,138 (-)NCBINCBI36hg18NCBI36
Build 34926,894,517 - 26,925,207NCBI
Celera926,831,534 - 26,875,621 (-)NCBI
Cytogenetic Map9p21.2NCBI
HuRef926,856,258 - 26,900,343 (-)NCBIHuRef
CHM1_1926,903,156 - 26,947,250 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on PLAA
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 737277
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.