Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: TNFRSF1A (TNF receptor superfamily member 1A) Homo sapiens
Analyze
Symbol: TNFRSF1A
Name: TNF receptor superfamily member 1A
Description: Exhibits identical protein binding activity and tumor necrosis factor binding activity. Involved in several processes, including cellular response to mechanical stimulus; positive regulation of signal transduction; and tumor necrosis factor-mediated signaling pathway. Localizes to several cellular components, including the Golgi membrane; extracellular space; and membrane raft. Implicated in several diseases, including IgA glomerulonephritis; Legionnaires' disease; acne; allergic bronchopulmonary aspergillosis; and autosomal dominant familial periodic fever. Biomarker of several diseases, including Behcet's disease; acquired immunodeficiency syndrome; female reproductive organ cancer (multiple); kidney disease (multiple); and lung disease (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CD120a; FPF; MGC19588; MS5; p55; p55-R; p60; TBP1; TNF-R; TNF-R-I; TNF-R1; TNF-R55; TNF-RI; TNFAR; TNFR-I; TNFR1; TNFR1-d2; TNFR55; TNFR60; tumor necrosis factor binding protein 1; tumor necrosis factor receptor 1; tumor necrosis factor receptor 1A isoform beta; tumor necrosis factor receptor superfamily member 1A; tumor necrosis factor receptor superfamily, member 1A; tumor necrosis factor receptor type 1; tumor necrosis factor receptor type I; tumor necrosis factor-alpha receptor
Orthologs:
Mus musculus (house mouse) : Tnfrsf1a (tumor necrosis factor receptor superfamily, member 1a)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tnfrsf1a (TNF receptor superfamily member 1A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tnfrsf1a (TNF receptor superfamily member 1A)
Pan paniscus (bonobo/pygmy chimpanzee) : TNFRSF1A (TNF receptor superfamily member 1A)
Canis lupus familiaris (dog) : TNFRSF1A (TNF receptor superfamily member 1A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tnfrsf1a (TNF receptor superfamily member 1A)
Sus scrofa (pig) : TNFRSF1A (TNF receptor superfamily member 1A)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38126,328,771 - 6,342,076 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37126,437,923 - 6,451,283 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36126,308,184 - 6,321,522 (-)NCBINCBI36hg18NCBI36
Build 34126,308,184 - 6,321,522NCBI
Celera128,054,567 - 8,067,927 (-)NCBI
Cytogenetic Map12p13.31NCBI
HuRef126,291,179 - 6,304,533 (-)NCBIHuRef
CHM1_1126,437,153 - 6,450,509 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on TNFRSF1A
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 737288
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-11-13
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.