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Gene: KMO (kynurenine 3-monooxygenase) Homo sapiens
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Symbol: KMO
Name: kynurenine 3-monooxygenase
Description: Exhibits FAD binding activity; NAD(P)H oxidase (H(2)O(2)-forming activity; and kynurenine 3-monooxygenase activity. Involved in NAD metabolic process; kynurenine metabolic process; and response to salt stress. Predicted to localize to mitochondrial outer membrane. Biomarker of schizophrenia.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: dJ317G22.1; kynurenine 3-hydroxylase; kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
Orthologs:
Mus musculus (house mouse) : Kmo (kynurenine 3-monooxygenase (kynurenine 3-hydroxylase))  MGI  Alliance
Rattus norvegicus (Norway rat) : Kmo (kynurenine 3-monooxygenase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kmo (kynurenine 3-monooxygenase)
Pan paniscus (bonobo/pygmy chimpanzee) : KMO (kynurenine 3-monooxygenase)
Canis lupus familiaris (dog) : KMO (kynurenine 3-monooxygenase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kmo (kynurenine 3-monooxygenase)
Sus scrofa (pig) : KMO (kynurenine 3-monooxygenase)
Chlorocebus sabaeus (African green monkey) : KMO (kynurenine 3-monooxygenase)
Heterocephalus glaber (naked mole-rat) : Kmo (kynurenine 3-monooxygenase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1241,532,134 - 241,595,642 (+)EnsemblGRCh38hg38GRCh38
GRCh381241,531,883 - 241,595,642 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371241,695,324 - 241,758,949 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361239,762,330 - 239,825,566 (+)NCBINCBI36hg18NCBI36
Build 341238,021,747 - 238,084,984NCBI
Celera1214,950,683 - 215,013,947 (+)NCBI
Cytogenetic Map1q43NCBI
HuRef1212,153,669 - 212,217,265 (+)NCBIHuRef
CHM1_11242,968,145 - 243,031,623 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on KMO
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 737300
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.