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Gene: PRPS2 (phosphoribosyl pyrophosphate synthetase 2) Homo sapiens
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Symbol: PRPS2
Name: phosphoribosyl pyrophosphate synthetase 2
Description: This gene encodes a phosphoribosyl pyrophosphate synthetase that plays a central role in the synthesis of purines and pyrimidines. The encoded protein catalyzes the synthesis of 5-phosphoribosyl 1-pyrophosphate from ATP and D-ribose 5-phosphate. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: phosphoribosyl pyrophosphate synthase II; PPRibP synthetase; PRS-II; PRSII; ribose-phosphate diphosphokinase 2; ribose-phosphate pyrophosphokinase 2; testicular secretory protein Li 41
Orthologs:
Mus musculus (house mouse) : Prps2 (phosphoribosyl pyrophosphate synthetase 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Prps2 (phosphoribosyl pyrophosphate synthetase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prps2 (phosphoribosyl pyrophosphate synthetase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PRPS2 (phosphoribosyl pyrophosphate synthetase 2)
Canis lupus familiaris (dog) : PRPS2 (phosphoribosyl pyrophosphate synthetase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prps2 (phosphoribosyl pyrophosphate synthetase 2)
Sus scrofa (pig) : PRPS2 (phosphoribosyl pyrophosphate synthetase 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X12,791,355 - 12,824,227 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X12,809,474 - 12,842,346 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X12,719,414 - 12,752,264 (+)NCBINCBI36hg18NCBI36
Build 34X12,569,187 - 12,601,996NCBI
CeleraX16,923,480 - 16,956,355 (+)NCBI
Cytogenetic MapXp22.2NCBI
HuRefX10,576,287 - 10,608,838 (+)NCBIHuRef
CHM1_1X12,839,890 - 12,872,768 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on PRPS2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 737326
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.