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Gene: ALDOB (aldolase, fructose-bisphosphate B) Homo sapiens
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Symbol: ALDOB
Name: aldolase, fructose-bisphosphate B
Description: Exhibits several functions, including ATPase binding activity; aldehyde-lyase activity; and fructose binding activity. Involved in several processes, including NADH oxidation; fructose 1,6-bisphosphate metabolic process; and vacuolar proton-transporting V-type ATPase complex assembly. Localizes to the centriolar satellite. Implicated in hereditary fructose intolerance syndrome and type 2 diabetes mellitus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ALDB; ALDO2; aldolase 2; aldolase B, fructose-bisphosphatase; aldolase B, fructose-bisphosphate; fructose-bisphosphate aldolase B; liver-type aldolase
Orthologs:
Mus musculus (house mouse) : Aldob (aldolase B, fructose-bisphosphate)  MGI  Alliance
Rattus norvegicus (Norway rat) : Aldob (aldolase, fructose-bisphosphate B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Aldob (aldolase, fructose-bisphosphate B)
Pan paniscus (bonobo/pygmy chimpanzee) : ALDOB (aldolase, fructose-bisphosphate B)
Canis lupus familiaris (dog) : ALDOB (aldolase, fructose-bisphosphate B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Aldob (aldolase, fructose-bisphosphate B)
Sus scrofa (pig) : ALDOB (aldolase, fructose-bisphosphate B)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389101,420,560 - 101,435,774 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh379104,182,842 - 104,198,062 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369103,223,479 - 103,237,926 (-)NCBINCBI36hg18NCBI36
Build 349101,263,213 - 101,277,660NCBI
Celera974,696,447 - 74,711,667 (-)NCBI
Cytogenetic Map9q31.1NCBI
HuRef973,782,293 - 73,797,509 (-)NCBIHuRef
CHM1_19104,329,256 - 104,344,476 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on ALDOB
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 737371
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.