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Gene: ALDOB (aldolase, fructose-bisphosphate B) Homo sapiens
Symbol: ALDOB
Name: aldolase, fructose-bisphosphate B
Description: Exhibits several functions, including ATPase binding activity; aldehyde-lyase activity; and fructose binding activity. Involved in several processes, including NADH oxidation; fructose 1,6-bisphosphate metabolic process; and vacuolar proton-transporting V-type ATPase complex assembly. Localizes to the centriolar satellite. Implicated in hereditary fructose intolerance syndrome and type 2 diabetes mellitus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ALDB; ALDO2; aldolase 2; aldolase B, fructose-bisphosphatase; aldolase B, fructose-bisphosphate; fructose-bisphosphate aldolase B; liver-type aldolase
Mus musculus (house mouse) : Aldob (aldolase B, fructose-bisphosphate)  MGI  Alliance
Rattus norvegicus (Norway rat) : Aldob (aldolase, fructose-bisphosphate B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Aldob (aldolase, fructose-bisphosphate B)
Pan paniscus (bonobo/pygmy chimpanzee) : ALDOB (aldolase, fructose-bisphosphate B)
Canis lupus familiaris (dog) : ALDOB (aldolase, fructose-bisphosphate B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Aldob (aldolase, fructose-bisphosphate B)
Sus scrofa (pig) : ALDOB (aldolase, fructose-bisphosphate B)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh389101,420,560 - 101,435,774 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh379104,182,842 - 104,198,062 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369103,223,479 - 103,237,926 (-)NCBINCBI36hg18NCBI36
Build 349101,263,213 - 101,277,660NCBI
Celera974,696,447 - 74,711,667 (-)NCBI
Cytogenetic Map9q31.1NCBI
HuRef973,782,293 - 73,797,509 (-)NCBIHuRef
CHM1_19104,329,256 - 104,344,476 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ALDOB
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 737371
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.