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Gene: IL3 (interleukin 3) Homo sapiens
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Symbol: IL3
Name: interleukin 3
Description: Predicted to have interleukin-3 receptor binding activity. Involved in embryonic hemopoiesis; positive regulation of cell population proliferation; and positive regulation of tyrosine phosphorylation of STAT protein. Predicted to localize to the extracellular space. Implicated in Graves' disease; asthma; and rheumatoid arthritis. Biomarker of several diseases, including Alzheimer's disease; Ebola hemorrhagic fever; genital herpes; major depressive disorder; and obesity.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: colony-stimulating factor, multiple; hematopoietic growth factor; IL-3; interleukin-3; mast cell growth factor; mast-cell growth factor; MCGF; MGC79398; MGC79399; MULTI-CSF; multilineage-colony-stimulating factor; multipotential colony-stimulating factor; P-cell stimulating factor; P-cell-stimulating factor
Orthologs:
Mus musculus (house mouse) : Il3 (interleukin 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Il3 (interleukin 3)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : IL3 (interleukin 3)
Canis lupus familiaris (dog) : IL3 (interleukin 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il3 (interleukin 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385132,060,655 - 132,063,204 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh375131,396,347 - 131,398,896 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365131,424,246 - 131,426,795 (+)NCBINCBI36hg18NCBI36
Build 345131,424,245 - 131,426,795NCBI
Celera5127,526,422 - 127,528,971 (+)NCBI
Cytogenetic Map5q31.1NCBI
HuRef5126,588,706 - 126,591,255 (+)NCBIHuRef
CHM1_15130,829,174 - 130,831,722 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on IL3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 737391
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.