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Gene: Pawr (PRKC, apoptosis, WT1, regulator) Mus musculus
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Symbol: Pawr
Name: PRKC, apoptosis, WT1, regulator
CRRD ID: 737403
Description: Predicted to have actin binding activity; enzyme binding activity; and leucine zipper domain binding activity. Involved in several processes, including negative regulation of cell population proliferation; regulation of cellular macromolecule biosynthetic process; and regulation of cellular response to stress. Localizes to cytoplasm and nuclear chromatin. Predicted to colocalize with actin filament. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human PAWR (pro-apoptotic WT1 regulator); PARTICIPATES IN ceramide signaling pathway; INTERACTS WITH 1H-pyrazole; 2-butoxyethanol; 4-hydroxyphenyl retinamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2310001G03Rik; P; Pa; Par-4; PAR4; PRKC apoptosis WT1 regulator protein; prostate apoptosis response 4 protein; RIKEN cDNA 2310001G03 gene
Orthologs:
Homo sapiens (human) : PAWR (pro-apoptotic WT1 regulator)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pawr (pro-apoptotic WT1 regulator)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pawr (pro-apoptotic WT1 regulator)
Pan paniscus (bonobo/pygmy chimpanzee) : PAWR (pro-apoptotic WT1 regulator)
Canis lupus familiaris (dog) : PAWR (pro-apoptotic WT1 regulator)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pawr (pro-apoptotic WT1 regulator)
Sus scrofa (pig) : PAWR (pro-apoptotic WT1 regulator)
Chlorocebus sabaeus (African green monkey) : PAWR (pro-apoptotic WT1 regulator)
Heterocephalus glaber (naked mole-rat) : Pawr (pro-apoptotic WT1 regulator)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910108,168,050 - 108,250,708 (+)NCBI
GRCm3810108,332,189 - 108,414,391 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10108,332,121 - 108,414,240 (+)EnsemblGRCm38mm10GRCm38
MGSCv3710107,769,245 - 107,851,447 (+)NCBIGRCm37mm9NCBIm37
MGSCv3610107,736,299 - 107,817,863 (+)NCBImm8
Celera10110,266,638 - 110,348,648 (+)NCBICelera
Cytogenetic Map10D1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Pawr
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 737403
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.