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Gene: DDX39B (DExD-box helicase 39B) Homo sapiens
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Symbol: DDX39B
Name: DExD-box helicase 39B
Description: Exhibits several functions, including ATP-dependent protein binding activity; ATPase activity, coupled; and snRNA binding activity. Involved in several processes, including RNA metabolic process; negative regulation of DNA damage checkpoint; and viral mRNA export from host cell nucleus. Localizes to the nuclear speck; spliceosomal complex; and transcription export complex. Colocalizes with the U4 snRNP; U6 snRNP; and cytoplasm. Implicated in type 1 diabetes mellitus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 56 kDa U2AF65-associated protein; ATP-dependent RNA helicase p47; BAT1; D6S81E; DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B; DEAD box protein UAP56; DEAD-box helicase 39B; DEAD-box protein UAP56; HLA-B-associated transcript 1 protein; hla-b-associated transcript 1a; nuclear RNA helicase (DEAD family); spliceosome RNA helicase BAT1; spliceosome RNA helicase DDX39B; U2AF65-associated protein 56; UAP56
Orthologs:
Mus musculus (house mouse) : Ddx39b (DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ddx39b (DExD-box helicase 39B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ddx39b (DExD-box helicase 39B)
Pan paniscus (bonobo/pygmy chimpanzee) : DDX39B (DExD-box helicase 39B)
Canis lupus familiaris (dog) : DDX39B (DExD-box helicase 39B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ddx39b (DExD-box helicase 39B)
Sus scrofa (pig) : DDX39B (DExD-box helicase 39B)
more info ...
Related Pseudogenes: DDX39BP1   DDX39BP2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38631,530,226 - 31,542,003 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37631,497,996 - 31,510,252 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36631,605,975 - 31,618,204 (-)NCBINCBI36hg18NCBI36
Build 34631,605,974 - 31,617,904NCBI
Celera633,096,234 - 33,108,459 (-)NCBI
Cytogenetic Map6p21.33NCBI
HuRef631,284,705 - 31,296,997 (-)NCBIHuRef
CHM1_1631,500,137 - 31,512,390 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on DDX39B
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 737407
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.