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Gene: DDX39B (DExD-box helicase 39B) Homo sapiens
Symbol: DDX39B
Name: DExD-box helicase 39B
Description: Exhibits several functions, including ATP-dependent protein binding activity; ATPase activity, coupled; and snRNA binding activity. Involved in several processes, including RNA metabolic process; negative regulation of DNA damage checkpoint; and viral mRNA export from host cell nucleus. Localizes to the nuclear speck; spliceosomal complex; and transcription export complex. Colocalizes with the U4 snRNP; U6 snRNP; and cytoplasm. Implicated in type 1 diabetes mellitus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 56 kDa U2AF65-associated protein; ATP-dependent RNA helicase p47; BAT1; D6S81E; DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B; DEAD box protein UAP56; DEAD-box helicase 39B; DEAD-box protein UAP56; HLA-B-associated transcript 1 protein; hla-b-associated transcript 1a; nuclear RNA helicase (DEAD family); spliceosome RNA helicase BAT1; spliceosome RNA helicase DDX39B; U2AF65-associated protein 56; UAP56
Mus musculus (house mouse) : Ddx39b (DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ddx39b (DExD-box helicase 39B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ddx39b (DExD-box helicase 39B)
Pan paniscus (bonobo/pygmy chimpanzee) : DDX39B (DExD-box helicase 39B)
Canis lupus familiaris (dog) : DDX39B (DExD-box helicase 39B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ddx39b (DExD-box helicase 39B)
Sus scrofa (pig) : DDX39B (DExD-box helicase 39B)
more info ...
Related Pseudogenes: DDX39BP1   DDX39BP2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38631,530,226 - 31,542,003 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37631,497,996 - 31,510,252 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36631,605,975 - 31,618,204 (-)NCBINCBI36hg18NCBI36
Build 34631,605,974 - 31,617,904NCBI
Celera633,096,234 - 33,108,459 (-)NCBI
Cytogenetic Map6p21.33NCBI
HuRef631,284,705 - 31,296,997 (-)NCBIHuRef
CHM1_1631,500,137 - 31,512,390 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on DDX39B
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 737407
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.