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Gene: MEGF8 (multiple EGF like domains 8) Homo sapiens
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Symbol: MEGF8
Name: multiple EGF like domains 8
Description: Predicted to have calcium ion binding activity. Involved in several processes, including craniofacial suture morphogenesis; gastrulation; and left/right pattern formation. Localizes to the extracellular exosome. Implicated in Carpenter syndrome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C19orf49; chromosome 19 open reading frame 49; CRPT2; EGF-like domain-containing protein 4; EGF-like protein 4; EGF-like-domain, multiple 4; EGFL4; epidermal growth factor-like protein 4; FLJ22365; HBV pre s2 binding protein 1; HBV pre-s2 binding protein 1; HBV pre-S2-binding protein 1; hepatitis B virus pre-S2-binding protein 1; MGC120684; MGC138147; multiple EGF-like domain protein 4; multiple EGF-like domains protein 8; multiple EGF-like-domains 8; multiple epidermal growth factor-like domains 8; multiple epidermal growth factor-like domains protein 8; Putative uncharacterized protein C19orf49; SBP1
Orthologs:
Mus musculus (house mouse) : Megf8 (multiple EGF-like-domains 8)  MGI  Alliance
Rattus norvegicus (Norway rat) : Megf8 (multiple EGF-like-domains 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Megf8 (multiple EGF like domains 8)
Pan paniscus (bonobo/pygmy chimpanzee) : MEGF8 (multiple EGF like domains 8)
Canis lupus familiaris (dog) : MEGF8 (multiple EGF like domains 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Megf8 (multiple EGF like domains 8)
Sus scrofa (pig) : MEGF8 (multiple EGF like domains 8)
Chlorocebus sabaeus (African green monkey) : MEGF8 (multiple EGF like domains 8)
Heterocephalus glaber (naked mole-rat) : Megf8 (multiple EGF like domains 8)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1942,325,609 - 42,378,769 (+)EnsemblGRCh38hg38GRCh38
GRCh381942,325,635 - 42,378,765 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371942,829,730 - 42,882,921 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361947,521,601 - 47,574,761 (+)NCBINCBI36hg18NCBI36
Build 341947,532,797 - 47,573,778NCBI
Celera1939,630,557 - 39,683,710 (+)NCBI
Cytogenetic Map19q13.2NCBI
HuRef1939,259,903 - 39,313,054 (+)NCBIHuRef
CHM1_11942,831,424 - 42,884,572 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on MEGF8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 737434
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.