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Gene: IER5 (immediate early response 5) Homo sapiens
Symbol: IER5
Name: immediate early response 5
Description: Exhibits identical protein binding activity. Involved in several processes, including cellular response to heat; positive regulation of cellular response to heat; and positive regulation of transcription by RNA polymerase II. Localizes to the cytoplasm; nucleolus; and nucleoplasm. Colocalizes with the protein phosphatase type 2A complex.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: immediate early response gene 5 protein; MGC102760; SBBI48
Mus musculus (house mouse) : Ier5 (immediate early response 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ier5 (immediate early response 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ier5 (immediate early response 5)
Pan paniscus (bonobo/pygmy chimpanzee) : IER5 (immediate early response 5)
Canis lupus familiaris (dog) : IER5 (immediate early response 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ier5 (immediate early response 5)
Sus scrofa (pig) : IER5 (immediate early response 5)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1181,088,700 - 181,092,900 (+)Ensembl
GRCh381181,088,700 - 181,092,900 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371181,057,638 - 181,059,979 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361179,324,261 - 179,326,602 (+)NCBINCBI36hg18NCBI36
Build 341177,789,294 - 177,791,629NCBI
Celera1154,164,524 - 154,166,865 (+)NCBI
Cytogenetic Map1q25.3NCBI
HuRef1152,288,717 - 152,291,058 (+)NCBIHuRef
CHM1_11182,480,274 - 182,482,615 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on IER5
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 737469
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.