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Gene: XYLT1 (xylosyltransferase 1) Homo sapiens
Symbol: XYLT1
Name: xylosyltransferase 1
Description: This locus encodes a xylosyltransferase enzyme. The encoded protein catalyzes transfer of UDP-xylose to serine residues of an acceptor protein substrate. This transfer reaction is necessary for biosynthesis of glycosaminoglycan chains. Mutations in this gene have been associated with increased severity of pseudoxanthoma elasticum.[provided by RefSeq, Nov 2009]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: beta-D-xylosyltransferase 1; DBQD2; O-xylosyltransferase 1; peptide O-xylosyltransferase 1; PXYLT1; XT-I; XT1; XTI; xylosyltransferase I; xylosyltransferase iota; xylT-I; XYLTI
Mus musculus (house mouse) : Xylt1 (xylosyltransferase 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Xylt1 (xylosyltransferase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Xylt1 (xylosyltransferase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : XYLT1 (xylosyltransferase 1)
Canis lupus familiaris (dog) : XYLT1 (xylosyltransferase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Xylt1 (xylosyltransferase 1)
Sus scrofa (pig) : XYLT1 (xylosyltransferase 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381617,102,324 - 17,470,881 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371617,196,181 - 17,564,738 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361617,103,682 - 17,472,239 (-)NCBINCBI36hg18NCBI36
Build 341617,108,839 - 17,472,239NCBI
Celera1616,738,145 - 17,106,289 (-)NCBI
Cytogenetic Map16p12.3NCBI
HuRef1616,198,445 - 16,453,510 (-)NCBIHuRef
CHM1_11617,283,444 - 17,652,050 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on XYLT1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 737486
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-07-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.