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Gene: SYP (synaptophysin) Homo sapiens
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Symbol: SYP
Name: synaptophysin
Description: This gene encodes an integral membrane protein of small synaptic vesicles in brain and endocrine cells. The protein also binds cholesterol and is thought to direct targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments. Mutations in this gene are associated with an X-linked form of cognitive disability. [provided by RefSeq, Jul 2017]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: major synaptic vesicle protein P38; MRX96; MRXSYP
Orthologs:
Mus musculus (house mouse) : Syp (synaptophysin)  MGI  Alliance
Rattus norvegicus (Norway rat) : Syp (synaptophysin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Syp (synaptophysin)
Pan paniscus (bonobo/pygmy chimpanzee) : SYP (synaptophysin)
Canis lupus familiaris (dog) : SYP (synaptophysin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Syp (synaptophysin)
Sus scrofa (pig) : SYP (synaptophysin)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X49,187,812 - 49,200,202 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X49,044,263 - 49,056,661 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X48,931,209 - 48,943,605 (-)NCBINCBI36hg18NCBI36
Build 34X48,800,635 - 48,813,032NCBI
CeleraX52,607,708 - 52,620,104 (+)NCBI
Cytogenetic MapXp11.23NCBI
HuRefX46,701,336 - 46,713,608 (-)NCBIHuRef
CHM1_1X49,076,586 - 49,088,982 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on SYP
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 737494
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.