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Gene: CEL (carboxyl ester lipase) Homo sapiens
Symbol: CEL
Name: carboxyl ester lipase
Description: Predicted to have lipase activity; neurexin family protein binding activity; and signaling receptor activity. Involved in cholesterol catabolic process and pancreatic juice secretion. Localizes to the extracellular exosome. Implicated in lipomatosis; maturity-onset diabetes of the young type 8; type 1 diabetes mellitus; and type 2 diabetes mellitus. Biomarker of type 1 diabetes mellitus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BAL; bile salt-activated lipase; bile salt-dependent lipase, oncofetal isoform; bile-salt-activated lipase; BSDL; BSSL; bucelipase; carboxyl ester hydrolase; carboxyl ester lipase (bile salt-stimulated lipase); CEase; CELL; cholesterol esterase; FAP; FAPP; fetoacinar pancreatic protein; LIPA; lysophospholipase, pancreatic; MODY8; pancreatic lysophospholipase; sterol esterase
Mus musculus (house mouse) : Cel (carboxyl ester lipase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cel (carboxyl ester lipase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cel (carboxyl ester lipase)
Pan paniscus (bonobo/pygmy chimpanzee) : CEL (carboxyl ester lipase)
Canis lupus familiaris (dog) : CEL (carboxyl ester lipase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cel (carboxyl ester lipase)
Sus scrofa (pig) : CEL (carboxyl ester lipase)
Chlorocebus sabaeus (African green monkey) : CEL (carboxyl ester lipase)
more info ...
Related Pseudogenes: CELP  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl9133,061,978 - 133,071,863 (+)Ensembl
GRCh38 Ensembl9133,061,978 - 133,071,861 (+)Ensembl
GRCh389133,061,981 - 133,071,861 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh379135,936,741 - 135,947,250 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369134,927,186 - 134,937,069 (+)NCBINCBI36hg18NCBI36
Build 349132,966,918 - 132,976,801NCBI
Celera9106,479,095 - 106,504,472 (+)NCBI
Cytogenetic Map9q34.13NCBI
HuRef9105,431,068 - 105,440,909 (+)NCBIHuRef
CHM1_19136,087,941 - 136,097,924 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on CEL
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 737498
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-01-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.