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Gene: Gnb1 (guanine nucleotide binding protein (G protein), beta 1) Mus musculus
Symbol: Gnb1
Name: guanine nucleotide binding protein (G protein), beta 1
Description: Predicted to have several functions, including GTPase activity; alkylglycerophosphoethanolamine phosphodiesterase activity; and spectrin binding activity. Involved in several processes, including phospholipase C-activating G protein-coupled receptor signaling pathway; retina development in camera-type eye; and sensory perception of taste. Localizes to heterotrimeric G-protein complex and photoreceptor outer segment. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia and autosomal dominant non-syndromic intellectual disability 42. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and hemolymphoid system gland. Orthologous to human GNB1 (G protein subunit beta 1); PARTICIPATES IN adenosine signaling pathway; dopamine signaling pathway via D1 family of receptors; eicosanoid signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; Aroclor 1254; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AA409223; C77571; Gnb-1; guanine nucleotide binding protein, beta 1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; MGC98074; transducin beta chain 1
Homo sapiens (human) : GNB1 (G protein subunit beta 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Gnb1 (G protein subunit beta 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gnb1 (G protein subunit beta 1)
Pan paniscus (bonobo/pygmy chimpanzee) : GNB1 (G protein subunit beta 1)
Canis lupus familiaris (dog) : GNB1 (G protein subunit beta 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gnb1 (G protein subunit beta 1)
Sus scrofa (pig) : GNB1 (G protein subunit beta 1)
Chlorocebus sabaeus (African green monkey) : GNB1 (G protein subunit beta 1)
Heterocephalus glaber (naked mole-rat) : Gnb1 (G protein subunit beta 1)
more info ...
Related Pseudogenes: Gnb1-ps2   Gnb1-ps3  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl4155,491,361 - 155,559,269 (+)EnsemblGRCm38mm10GRCm38
GRCm384155,491,300 - 155,559,269 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv374154,865,470 - 154,933,378 (+)NCBIGRCm37mm9NCBIm37
MGSCv364154,335,170 - 154,401,618 (+)NCBImm8
Celera4157,766,104 - 157,834,163 (+)NCBICelera
Cytogenetic Map4E2NCBI
cM Map486.17NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Gnb1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 737510
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-05-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.