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Gene: Gnb1 (guanine nucleotide binding protein (G protein), beta 1) Mus musculus
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Symbol: Gnb1
Name: guanine nucleotide binding protein (G protein), beta 1
Description: Predicted to have several functions, including GTPase activity; alkylglycerophosphoethanolamine phosphodiesterase activity; and spectrin binding activity. Involved in several processes, including phospholipase C-activating G protein-coupled receptor signaling pathway; retina development in camera-type eye; and sensory perception of taste. Localizes to heterotrimeric G-protein complex and photoreceptor outer segment. Human ortholog(s) of this gene implicated in acute lymphoblastic leukemia and autosomal dominant non-syndromic intellectual disability 42. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and hemolymphoid system gland. Orthologous to human GNB1 (G protein subunit beta 1); PARTICIPATES IN adenosine signaling pathway; dopamine signaling pathway via D1 family of receptors; eicosanoid signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; Aroclor 1254; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AA409223; C77571; Gnb-1; guanine nucleotide binding protein, beta 1; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; MGC98074; transducin beta chain 1
Orthologs:
Homo sapiens (human) : GNB1 (G protein subunit beta 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Gnb1 (G protein subunit beta 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gnb1 (G protein subunit beta 1)
Pan paniscus (bonobo/pygmy chimpanzee) : GNB1 (G protein subunit beta 1)
Canis lupus familiaris (dog) : GNB1 (G protein subunit beta 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gnb1 (G protein subunit beta 1)
Sus scrofa (pig) : GNB1 (G protein subunit beta 1)
Chlorocebus sabaeus (African green monkey) : GNB1 (G protein subunit beta 1)
Heterocephalus glaber (naked mole-rat) : Gnb1 (G protein subunit beta 1)
more info ...
Related Pseudogenes: Gnb1-ps2   Gnb1-ps3  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl4155,491,361 - 155,559,269 (+)EnsemblGRCm38mm10GRCm38
GRCm384155,491,300 - 155,559,269 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv374154,865,470 - 154,933,378 (+)NCBIGRCm37mm9NCBIm37
MGSCv364154,335,170 - 154,401,618 (+)NCBImm8
Celera4157,766,104 - 157,834,163 (+)NCBICelera
Cytogenetic Map4E2NCBI
cM Map486.17NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Gnb1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 737510
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-05-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.