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Gene: OPRM1 (opioid receptor mu 1) Homo sapiens
Symbol: OPRM1
Name: opioid receptor mu 1
Description: Exhibits G-protein alpha-subunit binding activity and beta-endorphin receptor activity. Involved in several processes, including regulation of cAMP-mediated signaling; regulation of cytosolic calcium ion concentration; and regulation of nitric oxide biosynthetic process. Predicted to localize to several cellular components, including the axon; dendrite; and endosome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: hMOP; KIAA0403; LMOR; M-OR-1; micro opioid receptor isoform hMOR-1A2; MOP; MOR; MOR1; mu opiate receptor; mu opioid receptor hMOR-1a; mu opioid receptor splice variant hMOR-1b; mu opioid receptor splice variant hMOR-1S; mu opioid receptor splice variant hMOR-1Y2; mu opioid receptor splice variant hMOR-1Y3; mu opioid receptor splice variant hMOR-1Z; mu-type opioid receptor; opioid receptor, mu 1; OPRM
Mus musculus (house mouse) : Oprm1 (opioid receptor, mu 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Oprm1 (opioid receptor, mu 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Oprm1 (opioid receptor mu 1)
Pan paniscus (bonobo/pygmy chimpanzee) : OPRM1 (opioid receptor mu 1)
Canis lupus familiaris (dog) : OPRM1 (opioid receptor mu 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Oprm1 (opioid receptor mu 1)
Sus scrofa (pig) : OPRM1 (opioid receptor mu 1)
Chlorocebus sabaeus (African green monkey) : OPRM1 (opioid receptor mu 1)
Heterocephalus glaber (naked mole-rat) : Oprm1 (opioid receptor mu 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl6154,010,496 - 154,246,867 (+)EnsemblGRCh38hg38GRCh38
GRCh386154,010,496 - 154,246,867 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh376154,331,631 - 154,568,001 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366154,402,136 - 154,609,693 (+)NCBINCBI36hg18NCBI36
Build 346154,452,556 - 154,660,114NCBI
Celera6155,066,098 - 155,302,376 (+)NCBI
Cytogenetic Map6q25.2NCBI
HuRef6151,895,214 - 152,131,143 (+)NCBIHuRef
CHM1_16154,595,701 - 154,831,638 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on OPRM1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 737513
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.