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Gene: Capn2 (calpain 2) Mus musculus
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Symbol: Capn2
Name: calpain 2
Description: Exhibits calcium-dependent cysteine-type endopeptidase activity. Involved in several processes, including blastocyst development; cellular response to amino acid stimulus; and myoblast fusion. Localizes to several cellular components, including the chromatin; cytosol; and lysosome. Predicted to colocalize with the mitochondrial intermembrane space. Is expressed in several structures, including hindbrain; lens epithelium; oral region epithelium; skin; and spinal cord floor plate. Orthologous to human CAPN2 (calpain 2); PARTICIPATES IN the proteolytic pathway involving calcium-dependent proteases; Alzheimer's disease pathway; apoptotic cell death pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-di-tert-butyl-4-methylphenol; 4-\{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino\}benzoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 80 kDa M-calpain subunit; AI326419; calcium-activated neutral proteinase 2; CALP80; calpain M-type; calpain-2 catalytic subunit; calpain-2 large subunit; CANP 2; Capa-2; Capa2; cysteine proteinase; m-calpain; m-calpain 80 kDa large subunit; m-calpain large subunit; m-calpin; millimolar-calpain
Orthologs:
Homo sapiens (human) : CAPN2 (calpain 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Capn2 (calpain 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Capn2 (calpain 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CAPN2 (calpain 2)
Canis lupus familiaris (dog) : CAPN2 (calpain 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Capn2 (calpain 2)
Sus scrofa (pig) : CAPN2 (calpain 2)
Chlorocebus sabaeus (green monkey) : CAPN2 (calpain 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1182,467,260 - 182,517,608 (-)Ensembl
GRCm381182,467,253 - 182,517,610 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371184,397,390 - 184,447,614 (-)NCBIGRCm37mm9NCBIm37
MGSCv361184,303,935 - 184,354,199 (-)NCBImm8
Celera1189,509,702 - 189,560,154 (-)NCBICelera
Cytogenetic Map1 H5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Capn2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 737526
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.