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Gene: Ednra (endothelin receptor type A) Mus musculus
Symbol: Ednra
Name: endothelin receptor type A
Description: Exhibits endothelin receptor activity. Involved in several processes, including circulatory system development; neural crest cell development; and regulation of glucose transmembrane transport. Predicted to colocalize with membrane raft. Is expressed in several structures, including arterial system; branchial arch; central nervous system; genitourinary system; and heart. Used to study mandibulofacial dysostosis with alopecia and velocardiofacial syndrome. Human ortholog(s) of this gene implicated in hypertension (multiple); lung disease; mandibulofacial dysostosis with alopecia; migraine; and obstructive sleep apnea. Orthologous to human EDNRA (endothelin receptor type A); PARTICIPATES IN endothelin signaling pathway; inflammatory response pathway; Rho/Rac/Cdc42 mediated signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AEA001; endothelin A receptor; endothelin-1 receptor; ET-A; ET-AR; ETa; G-protein coupled receptor 10; Gpcr10; Mhdaaea1
Homo sapiens (human) : EDNRA (endothelin receptor type A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ednra (endothelin receptor type A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ednra (endothelin receptor type A)
Pan paniscus (bonobo/pygmy chimpanzee) : EDNRA (endothelin receptor type A)
Canis lupus familiaris (dog) : EDNRA (endothelin receptor type A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ednra (endothelin receptor type A)
Sus scrofa (pig) : EDNRA (endothelin receptor type A)
Chlorocebus sabaeus (African green monkey) : EDNRA (endothelin receptor type A)
Heterocephalus glaber (naked mole-rat) : Ednra (endothelin receptor type A)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl877,663,031 - 77,724,464 (-)EnsemblGRCm38mm10GRCm38
GRCm38877,663,029 - 77,724,452 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37880,186,928 - 80,248,351 (-)NCBIGRCm37mm9NCBIm37
MGSCv36880,559,140 - 80,620,420 (-)NCBImm8
Celera881,946,457 - 82,007,225 (-)NCBICelera
Cytogenetic Map8C1NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ednra
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 737538
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.