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Gene: Ednra (endothelin receptor type A) Mus musculus
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Symbol: Ednra
Name: endothelin receptor type A
Description: Exhibits endothelin receptor activity. Involved in several processes, including circulatory system development; neural crest cell development; and regulation of glucose transmembrane transport. Predicted to colocalize with membrane raft. Is expressed in several structures, including arterial system; branchial arch; central nervous system; genitourinary system; and heart. Used to study mandibulofacial dysostosis with alopecia and velocardiofacial syndrome. Human ortholog(s) of this gene implicated in hypertension (multiple); lung disease; mandibulofacial dysostosis with alopecia; migraine; and obstructive sleep apnea. Orthologous to human EDNRA (endothelin receptor type A); PARTICIPATES IN endothelin signaling pathway; inflammatory response pathway; Rho/Rac/Cdc42 mediated signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; all-trans-retinoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AEA001; endothelin A receptor; endothelin-1 receptor; ET-A; ET-AR; ETa; G-protein coupled receptor 10; Gpcr10; Mhdaaea1
Orthologs:
Homo sapiens (human) : EDNRA (endothelin receptor type A)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ednra (endothelin receptor type A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ednra (endothelin receptor type A)
Pan paniscus (bonobo/pygmy chimpanzee) : EDNRA (endothelin receptor type A)
Canis lupus familiaris (dog) : EDNRA (endothelin receptor type A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ednra (endothelin receptor type A)
Sus scrofa (pig) : EDNRA (endothelin receptor type A)
Chlorocebus sabaeus (African green monkey) : EDNRA (endothelin receptor type A)
Heterocephalus glaber (naked mole-rat) : Ednra (endothelin receptor type A)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl877,663,031 - 77,724,464 (-)EnsemblGRCm38mm10GRCm38
GRCm38877,663,029 - 77,724,452 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37880,186,928 - 80,248,351 (-)NCBIGRCm37mm9NCBIm37
MGSCv36880,559,140 - 80,620,420 (-)NCBImm8
Celera881,946,457 - 82,007,225 (-)NCBICelera
Cytogenetic Map8C1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ednra
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 737538
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.