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Gene: Hcrtr1 (hypocretin (orexin) receptor 1) Mus musculus
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Symbol: Hcrtr1
Name: hypocretin (orexin) receptor 1
Description: Predicted to have orexin receptor activity and peptide hormone binding activity. Involved in positive regulation of ERK1 and ERK2 cascade. Predicted to localize to the integral component of plasma membrane. Is expressed in several structures, including brain; genitourinary system; gut; immune system; and liver and biliary system. Orthologous to human HCRTR1 (hypocretin receptor 1); PARTICIPATES IN G protein mediated signaling pathway via Galphaq family; orexin/hypocretin signaling pathway via orexin/hypocretin receptor 1; orexin/hypocretin signaling pathway; INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: hypocretin receptor type 1; MGC141357; orexin receptor type 1; ox-1-R; ox1-R; Ox1r
Orthologs:
Homo sapiens (human) : HCRTR1 (hypocretin receptor 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Hcrtr1 (hypocretin receptor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hcrtr1 (hypocretin receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : HCRTR1 (hypocretin receptor 1)
Canis lupus familiaris (dog) : HCRTR1 (hypocretin receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hcrtr1 (hypocretin receptor 1)
Sus scrofa (pig) : HCRTR1 (hypocretin receptor 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm384130,130,217 - 130,139,594 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv374129,807,461 - 129,816,406 (-)NCBIGRCm37mm9NCBIm37
MGSCv364129,632,521 - 129,641,466 (-)NCBImm8
Celera4128,464,692 - 128,473,445 (-)NCBICelera
Cytogenetic Map4 D2.2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Hcrtr1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 737545
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-11-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.