Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Hcrtr1 (hypocretin (orexin) receptor 1) Mus musculus
Symbol: Hcrtr1
Name: hypocretin (orexin) receptor 1
Description: Predicted to have orexin receptor activity and peptide hormone binding activity. Involved in positive regulation of ERK1 and ERK2 cascade. Predicted to localize to the integral component of plasma membrane. Is expressed in several structures, including brain; genitourinary system; gut; immune system; and liver and biliary system. Orthologous to human HCRTR1 (hypocretin receptor 1); PARTICIPATES IN G protein mediated signaling pathway via Galphaq family; orexin/hypocretin signaling pathway via orexin/hypocretin receptor 1; orexin/hypocretin signaling pathway; INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: hypocretin receptor type 1; MGC141357; orexin receptor type 1; ox-1-R; ox1-R; Ox1r
Homo sapiens (human) : HCRTR1 (hypocretin receptor 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Hcrtr1 (hypocretin receptor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hcrtr1 (hypocretin receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : HCRTR1 (hypocretin receptor 1)
Canis lupus familiaris (dog) : HCRTR1 (hypocretin receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hcrtr1 (hypocretin receptor 1)
Sus scrofa (pig) : HCRTR1 (hypocretin receptor 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm384130,130,217 - 130,139,594 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv374129,807,461 - 129,816,406 (-)NCBIGRCm37mm9NCBIm37
MGSCv364129,632,521 - 129,641,466 (-)NCBImm8
Celera4128,464,692 - 128,473,445 (-)NCBICelera
Cytogenetic Map4 D2.2NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Hcrtr1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 737545
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-11-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.