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Gene: Hadh (hydroxyacyl-Coenzyme A dehydrogenase) Mus musculus
Symbol: Hadh
Name: hydroxyacyl-Coenzyme A dehydrogenase
Description: Exhibits 3-hydroxyacyl-CoA dehydrogenase activity. Involved in positive regulation of cold-induced thermogenesis. Localizes to the mitochondrion. Human ortholog(s) of this gene implicated in familial hyperinsulinemic hypoglycemia 4. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Orthologous to human HADH (hydroxyacyl-CoA dehydrogenase); PARTICIPATES IN 2-aminoadipic 2-oxoadipic aciduria pathway; 3-hydroxyacyl-CoA dehydrogenase deficiency pathway; butanoate metabolic pathway; INTERACTS WITH (+)-dexrazoxane; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AA409008; AU019341; AW742602; Hadhsc; HCDH; hydroxyacyl-coenzyme A dehydrogenase, mitochondrial; hydroxylacyl-Coenzyme A dehydrogenase; hydroxylacyl-Coenzyme A dehydrogenase-dehydrogenase; L-3-hydroxyacyl-Coenzyme A dehydrogenase, short chain; medium and short chain L-3-hydroxyacyl-coenzyme A dehydrogenase; medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase; Schad; short chain 3-hydroxyacyl-CoA dehydrogenase; short-chain 3-hydroxyacyl-CoA dehydrogenase
Homo sapiens (human) : HADH (hydroxyacyl-CoA dehydrogenase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Hadh (hydroxyacyl-CoA dehydrogenase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hadh (hydroxyacyl-CoA dehydrogenase)
Pan paniscus (bonobo/pygmy chimpanzee) : HADH (hydroxyacyl-CoA dehydrogenase)
Canis lupus familiaris (dog) : HADH (hydroxyacyl-CoA dehydrogenase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hadh (hydroxyacyl-CoA dehydrogenase)
Sus scrofa (pig) : HADH (hydroxyacyl-CoA dehydrogenase)
Chlorocebus sabaeus (green monkey) : HADH (hydroxyacyl-CoA dehydrogenase)
Heterocephalus glaber (naked mole-rat) : Hadh (hydroxyacyl-CoA dehydrogenase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl3131,233,419 - 131,272,101 (-)Ensembl
GRCm383131,233,419 - 131,272,101 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv373130,936,342 - 130,974,955 (-)NCBIGRCm37mm9NCBIm37
MGSCv363131,222,610 - 131,261,182 (-)NCBImm8
Celera3137,754,691 - 137,793,317 (-)NCBICelera
Cytogenetic Map3 G3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Hadh
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 737567
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.