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Gene: SPN (sialophorin) Homo sapiens
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Symbol: SPN
Name: sialophorin
Description: Exhibits Hsp70 protein binding activity. Involved in several processes, including T-helper 1 cell lineage commitment; interferon-gamma production; and positive regulation of tumor necrosis factor biosynthetic process. Localizes to the cell surface and extracellular space.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CD43; galactoglycoprotein; GALGP; GPL115; leukocyte sialoglycoprotein; leukosialin; LSN; sialophorin (gpL115, leukosialin, CD43); sialophorin (leukosialin, CD43)
Orthologs:
Mus musculus (house mouse) : Spn (sialophorin)  MGI  Alliance
Rattus norvegicus (Norway rat) : Spn (sialophorin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Spn (sialophorin)
Pan paniscus (bonobo/pygmy chimpanzee) : SPN (sialophorin)
Canis lupus familiaris (dog) : SPN (sialophorin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Spn (sialophorin)
Sus scrofa (pig) : SPN (sialophorin)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1629,662,979 - 29,670,876 (+)Ensembl
GRCh381629,662,950 - 29,670,876 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371629,674,271 - 29,681,828 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361629,581,801 - 29,589,329 (+)NCBINCBI36hg18NCBI36
Build 34864,262,738 - 64,263,150NCBI
Celera1673,114,178 - 73,121,702 (-)NCBI
Cytogenetic Map16p11.2NCBI
HuRef1627,335,753 - 27,343,116 (+)NCBIHuRef
CHM1_11630,890,050 - 30,897,603 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on SPN
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 737577
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.