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Gene: ACVR2B (activin A receptor type 2B) Homo sapiens
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Symbol: ACVR2B
Name: activin A receptor type 2B
Description: Exhibits growth factor binding activity and protein serine/threonine kinase activity. Predicted to contribute to activin receptor activity, type II. Involved in several processes, including positive regulation of activin receptor signaling pathway; positive regulation of ossification; and transmembrane receptor protein serine/threonine kinase signaling pathway. Localizes to the cytoplasm and receptor complex. Implicated in visceral heterotaxy.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: activin A receptor type IIB; activin A receptor, type IIB; activin receptor type-2B; ActR-IIB; ACTRIIB; HTX4; MGC116908
Orthologs:
Mus musculus (house mouse) : Acvr2b (activin receptor IIB)  MGI  Alliance
Rattus norvegicus (Norway rat) : Acvr2b (activin A receptor type 2B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Acvr2b (activin A receptor type 2B)
Pan paniscus (bonobo/pygmy chimpanzee) : ACVR2B (activin A receptor type 2B)
Canis lupus familiaris (dog) : ACVR2B (activin A receptor type 2B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Acvr2b (activin A receptor type 2B)
Sus scrofa (pig) : ACVR2B (activin A receptor type 2B)
Chlorocebus sabaeus (African green monkey) : ACVR2B (activin A receptor type 2B)
Heterocephalus glaber (naked mole-rat) : Acvr2b (activin A receptor type 2B)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl338,453,890 - 38,493,142 (+)Ensembl
GRCh38338,453,890 - 38,493,142 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37338,495,790 - 38,534,633 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36338,470,794 - 38,509,637 (+)NCBINCBI36hg18NCBI36
Build 34338,470,813 - 38,499,868NCBI
Celera338,431,705 - 38,470,515 (+)NCBI
Cytogenetic Map3p22.2NCBI
HuRef338,561,058 - 38,576,879 (+)NCBIHuRef
CHM1_1338,447,458 - 38,486,272 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - uncurated

Genomics

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Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on ACVR2B
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 737613
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-01-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.