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Gene: PCSK1N (proprotein convertase subtilisin/kexin type 1 inhibitor) Homo sapiens
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Symbol: PCSK1N
Name: proprotein convertase subtilisin/kexin type 1 inhibitor
Description: The protein encoded by this gene functions as an inhibitor of prohormone convertase 1, which regulates the proteolytic cleavage of neuroendocrine peptide precursors. The proprotein is further processed into multiple short peptides. A polymorphism within this gene may be associated with obesity. [provided by RefSeq, Aug 2013]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BigLEN; granin-like neuroendocrine peptide; PEN; pro-SAAS; proprotein convertase 1 inhibitor; proSAAS; SAAS; SCG8; SgVIII
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X48,831,096 - 48,835,610 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X48,689,504 - 48,694,036 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X48,574,450 - 48,578,904 (-)NCBINCBI36hg18NCBI36
Build 34X48,445,755 - 48,450,209NCBI
CeleraX52,969,569 - 52,974,023 (+)NCBI
Cytogenetic MapXp11.23NCBI
HuRefX46,349,219 - 46,353,523 (-)NCBIHuRef
CHM1_1X48,720,644 - 48,725,174 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on PCSK1N
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 737617
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.