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Gene: KLRC4-KLRK1 (KLRC4-KLRK1 readthrough) Homo sapiens
Symbol: KLRC4-KLRK1
Name: KLRC4-KLRK1 readthrough
Description: Exhibits signaling receptor activity. Involved in several processes, including negative regulation of GTPase activity; negative regulation of natural killer cell chemotaxis; and positive regulation of natural killer cell mediated cytotoxicity. Localizes to cell surface and plasma membrane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: killer cell lectin-like receptor subfamily K member 1; NK cell receptor D; NKG2-D type II integral membrane protein; NKG2-D-activating NK receptor
Mus musculus (house mouse) : Clec2m (C-type lectin domain family 2, member m)  MGI  Alliance
Rattus norvegicus (Norway rat) : Klre1 (killer cell lectin-like receptor, family E, member 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : LOC102005691 (NKG2-D type II integral membrane protein)
Canis lupus familiaris (dog) : LOC100687968 (C-type lectin domain family 2 member F-like)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101976242 (NKG2-D type II integral membrane protein)
Sus scrofa (pig) : LOC100519314 (natural killer cells antigen CD94)
Chlorocebus sabaeus (African green monkey) : KLRK1 (killer cell lectin like receptor K1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1210,372,353 - 10,410,146 (-)EnsemblGRCh38hg38GRCh38
GRCh38 Ensembl1210,372,353 - 10,391,874 (-)EnsemblGRCh38hg38GRCh38
GRCh381210,372,353 - 10,410,146 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371210,524,952 - 10,562,745 (-)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map12p13.2NCBI
HuRef1210,267,379 - 10,305,170 (-)NCBIHuRef
CHM1_11210,494,385 - 10,532,177 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on KLRC4-KLRK1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 7380820
Created: 2013-10-22
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.