Gene: Kmt2b (lysine methyltransferase 2B) Rattus norvegicus
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Symbol: Kmt2b
Name: lysine methyltransferase 2B
Description: Predicted to have histone methyltransferase activity (H3-K4 specific); predicted to be involved in several processes, including gamete generation, gene silencing, and histone H3-K4 trimethylation; predicted to localize to the histone methyltransferase complex; orthologous to human KMT2B (lysine methyltransferase 2B); PARTICIPATES IN histone modification pathway; INTERACTS WITH bisphenol A; glyphosate; 17beta-estradiol (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: histone-lysine N-methyltransferase 2B-like; LOC102550344; LOC361543; LOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2B; lysine (K)-specific methyltransferase 2B; Mll4; myeloid/lymphoid or mixed-lineage leukemia 4; RGD1308331; similar to Trithorax homolog 2 (Mixed lineage leukemia gene homolog 2 protein); Wbp7; WW domain binding protein 7
Orthologs:
Homo sapiens (human) : KMT2B (lysine methyltransferase 2B)  HGNC  Alliance
Mus musculus (house mouse) : Kmt2b (lysine (K)-specific methyltransferase 2B)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kmt2b (lysine methyltransferase 2B)
Pan paniscus (bonobo/pygmy chimpanzee) : KMT2B (lysine methyltransferase 2B)
Canis lupus familiaris (dog) : KMT2B (lysine methyltransferase 2B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kmt2b (lysine methyltransferase 2B)
Sus scrofa (pig) : KMT2B (lysine methyltransferase 2B)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0189,022,889 - 89,042,176 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0190,177,704 - 90,197,879 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4185,613,847 - 85,633,136 (-)NCBIRGSC3.4rn4RGSC3.4
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Kmt2b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 7678027
Created: 2013-12-18
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.