Il1rn (interleukin 1 receptor antagonist) - Chinchilla Research Resource Database
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Gene: Il1rn (interleukin 1 receptor antagonist) Chinchilla lanigera
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Symbol: Il1rn
Name: interleukin 1 receptor antagonist
CRRD ID: 8763134
Description: ENCODES a protein that exhibits interleukin-1 receptor antagonist activity (ortholog); interleukin-1 receptor binding (ortholog); interleukin-1 type I receptor antagonist activity (ortholog); INVOLVED IN acute-phase response (ortholog); carboxylic acid metabolic process (ortholog); cellular response to norepinephrine stimulus (ortholog); PARTICIPATES IN interleukin-1 signaling pathway; ASSOCIATED WITH Abscess (ortholog); acute kidney failure (ortholog); Acute Liver Failure (ortholog); FOUND IN extracellular region (ortholog); extracellular space (ortholog); vesicle (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Orthologs:
Homo sapiens (human) : IL1RN (interleukin 1 receptor antagonist)  HGNC  Alliance
Mus musculus (house mouse) : Il1rn (interleukin 1 receptor antagonist)  MGI  Alliance
Rattus norvegicus (Norway rat) : Il1rn (interleukin 1 receptor antagonist)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100991079 (interleukin-1 receptor antagonist protein)
Canis lupus familiaris (dog) : IL1RN (interleukin 1 receptor antagonist)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il1rn (interleukin 1 receptor antagonist)
Sus scrofa (pig) : IL1RN (interleukin 1 receptor antagonist)
Chlorocebus sabaeus (African green monkey) : IL1RN (interleukin 1 receptor antagonist)
Heterocephalus glaber (naked mole-rat) : Il1rn (interleukin 1 receptor antagonist)
more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554701,144,810 - 1,159,471 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554701,145,022 - 1,159,413 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Abscess  (ISO)
acute kidney failure  (ISO)
Acute Liver Failure  (ISO)
Acute Lung Injury  (ISO)
Acute Necrotizing Pancreatitis  (ISO)
adult respiratory distress syndrome  (ISO)
allergic conjunctivitis  (ISO)
alopecia areata  (ISO)
Anorexia  (ISO)
anterior uveitis  (ISO)
anthracosis  (ISO)
anti-basement membrane glomerulonephritis  (ISO)
Arsenic Poisoning  (ISO)
asthma  (ISO)
Atrophy  (ISO)
autistic disorder  (ISO)
autoimmune thrombocytopenic purpura  (ISO)
autosomal dominant polycystic kidney disease  (ISO)
B-Cell Chronic Lymphocytic Leukemia  (ISO)
bacterial pneumonia  (ISO)
Behcet's disease  (ISO)
Brain Injuries  (ISO)
brain ischemia  (ISO)
Bronchial Hyperreactivity  (ISO)
bronchiolitis  (ISO)
bronchiolitis obliterans  (ISO)
Bronchopulmonary Dysplasia  (ISO)
bronchus carcinoma  (ISO)
Cachexia  (ISO)
calcium oxalate nephrolithiasis  (ISO)
cardiovascular system disease  (ISO)
Carotid Artery Injuries  (ISO)
Cerebral Hemorrhage  (ISO)
cerebrovascular disease  (ISO)
chronic kidney disease  (ISO)
chronic myeloid leukemia  (ISO)
chronic obstructive pulmonary disease  (ISO)
Chronic Rhinosinusitis  (ISO)
Chronic Uveitis  (ISO)
cicatricial pemphigoid  (ISO)
Colonic Neoplasms  (ISO)
common cold  (ISO)
Corneal Graft Rejection  (ISO)
corneal neovascularization  (ISO)
COVID-19  (ISO)
crescentic glomerulonephritis  (ISO)
Cryopyrin-Associated Periodic Syndromes  (ISO)
cystic fibrosis  (ISO)
dacryocystitis  (ISO)
Deficiency of Interleukin-1 Receptor Antagonist  (ISO)
Diabetes Mellitus, Experimental  (ISO)
diabetic angiopathy  (ISO)
Diabetic Nephropathies  (ISO)
diarrhea  (ISO)
Drug Hypersensitivity Syndrome  (ISO)
Drug-Induced Agranulocytosis  (ISO)
dry eye syndrome  (ISO)
encephalitis  (ISO)
end stage renal disease  (ISO)
Endotoxemia  (ISO)
Endotoxin-Induced Uveitis  (ISO)
exanthem  (ISO)
Experimental Arthritis  (ISO)
Experimental Autoimmune Encephalomyelitis  (ISO)
Experimental Autoimmune Myocarditis  (ISO)
Experimental Autoimmune Uveitis  (ISO)
Experimental Colitis  (ISO)
Extravasation of Diagnostic and Therapeutic Materials  (ISO)
Eye Manifestations  (ISO)
Febrile Seizures  (ISO)
Fever  (ISO)
fibromyalgia  (ISO)
Fibrosis  (ISO)
glomerulonephritis  (ISO)
gout  (ISO)
Graft vs Host Disease  (ISO)
Graves Ophthalmopathy  (ISO)
hairy cell leukemia  (ISO)
hemolytic-uremic syndrome  (ISO)
Henoch-Schoenlein purpura  (ISO)
hepatocellular carcinoma  (ISO)
hereditary diffuse gastric cancer  (ISO)
herpes simplex virus keratitis  (ISO)
Human Influenza  (ISO)
Hyperalgesia  (ISO)
hyperglycemia  (ISO)
hypertension  (ISO)
idiopathic pulmonary fibrosis  (ISO)
IgA glomerulonephritis  (ISO)
Inflammation  (ISO)
inflammatory bowel disease  (ISO)
interstitial lung disease  (ISO)
juvenile rheumatoid arthritis  (ISO)
keratoconus  (ISO)
kidney disease  (ISO)
Kidney Reperfusion Injury  (ISO)
learning disability  (ISO)
Leukocytosis  (ISO)
Lichen Sclerosus et Atrophicus  (ISO)
listeriosis  (ISO)
Liver Reperfusion Injury  (ISO)
lung non-small cell carcinoma  (ISO)
lupus nephritis  (ISO)
Mammary Neoplasms, Experimental  (ISO)
Meibomian Gland Dysfunction  (ISO)
melanoma  (ISO)
mental depression  (ISO)
middle cerebral artery infarction  (ISO)
morbid obesity  (ISO)
Muckle-Wells syndrome  (ISO)
mucositis  (ISO)
multiple myeloma  (ISO)
Multiple Organ Failure  (ISO)
multiple sclerosis  (ISO)
myocardial infarction  (ISO)
Myocardial Reperfusion Injury  (ISO)
myositis  (ISO)
Necrosis  (ISO)
Neoplasm Invasiveness  (ISO)
nephrotic syndrome  (ISO)
non-alcoholic fatty liver disease  (ISO)
obesity  (ISO)
Oligoanuria  (ISO)
osteoporosis  (ISO)
Pain  (ISO)
periodontitis  (ISO)
pleural disease  (ISO)
pleural tuberculosis  (ISO)
pleurisy  (ISO)
pneumonia  (ISO)
Postoperative Cognitive Dysfunction  (ISO)
pre-eclampsia  (ISO)
Proctocolitis  (ISO)
Prostatic Neoplasms  (ISO)
prostatitis  (ISO)
proteinuria  (ISO)
Pseudomonas Aeruginosa Keratitis  (ISO)
Pseudomonas Infections  (ISO)
pulmonary eosinophilia  (ISO)
pulmonary fibrosis  (ISO)
pulmonary hypertension  (ISO)
pulmonary sarcoidosis  (ISO)
pulmonary tuberculosis  (ISO)
pyelonephritis  (ISO)
renal cell carcinoma  (ISO)
respiratory allergy  (ISO)
rheumatoid arthritis  (ISO)
rhinitis  (ISO)
Schnitzler syndrome  (ISO)
sciatic neuropathy  (ISO)
Sclerosis  (ISO)
Sepsis  (ISO)
Serositis  (ISO)
silicosis  (ISO)
Sjogren's syndrome  (ISO)
skin disease  (ISO)
Spinal Cord Injuries  (ISO)
status epilepticus  (ISO)
Stomach Neoplasms  (ISO)
Stroke  (ISO)
Subarachnoid Hemorrhage  (ISO)
systemic lupus erythematosus  (ISO)
Tobacco Use Disorder  (ISO)
toxic shock syndrome  (ISO)
transient cerebral ischemia  (ISO)
Transplant Rejection  (ISO)
type 1 diabetes mellitus  (ISO)
type 2 diabetes mellitus  (ISO)
ulcerative colitis  (ISO)
ureteral obstruction  (ISO)
urinary bladder cancer  (ISO)
Urinary Calculi  (ISO)
Uveitis, Chronic Anterior  (ISO)
vascular disease  (ISO)
Venous Thrombosis  (ISO)
Ventilator-Induced Lung Injury  (ISO)
Viral Bronchiolitis  (ISO)
viral pneumonia  (ISO)


Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References


Genomics

Comparative Map Data
Il1rn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554701,144,810 - 1,159,471 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554701,145,022 - 1,159,413 (-)NCBIChiLan1.0ChiLan1.0
IL1RN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2113,107,214 - 113,134,016 (+)EnsemblGRCh38hg38GRCh38
GRCh382113,099,365 - 113,134,016 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372113,868,693 - 113,891,593 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362113,591,941 - 113,608,064 (+)NCBINCBI36hg18NCBI36
Build 342113,591,700 - 113,607,823NCBI
Celera2107,260,159 - 107,276,191 (+)NCBI
Cytogenetic Map2q14.1NCBI
HuRef2106,329,950 - 106,345,897 (+)NCBIHuRef
CHM1_12113,879,899 - 113,896,017 (+)NCBICHM1_1
Il1rn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39224,226,872 - 24,241,503 (+)NCBI
GRCm38224,336,860 - 24,351,491 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl224,336,853 - 24,351,494 (+)EnsemblGRCm38mm10GRCm38
MGSCv37224,192,380 - 24,207,011 (+)NCBIGRCm37mm9NCBIm37
MGSCv36224,158,869 - 24,173,490 (+)NCBImm8
Celera224,056,294 - 24,070,923 (+)NCBICelera
Cytogenetic Map2A3NCBI
cM Map216.36NCBI
Il1rn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.031,449,778 - 1,468,624 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl31,452,644 - 1,468,614 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.031,445,598 - 1,461,452 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.432,607,800 - 2,613,216 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.132,607,803 - 2,611,842 (+)NCBI
Celera31,959,290 - 1,964,693 (+)NCBICelera
Cytogenetic Map3p13NCBI
LOC100991079
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12A114,061,182 - 114,077,048 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A114,061,182 - 114,078,839 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02A88,991,646 - 89,008,013 (-)NCBI
IL1RN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1737,212,751 - 37,249,329 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11737,236,690 - 37,250,424 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Il1rn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049367831,447,158 - 1,466,331 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IL1RN
(Sus scrofa - pig)
No map positions available.
IL1RN
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl1416,146,333 - 16,151,326 (+)Ensembl
ChlSab1.11416,136,667 - 16,152,451 (+)NCBI
Il1rn
(Heterocephalus glaber - naked mole-rat)
No map positions available.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000007205   ⟹   ENSCLAP00000007093
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554701,144,810 - 1,159,471 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000007206   ⟹   ENSCLAP00000007094
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554701,146,458 - 1,159,359 (-)Ensembl
RefSeq Acc Id: XM_005400584   ⟹   XP_005400641
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554701,145,022 - 1,159,364 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005400585   ⟹   XP_005400642
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554701,145,022 - 1,150,898 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005400586   ⟹   XP_005400643
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554701,145,022 - 1,159,413 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013522846   ⟹   XP_013378300
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554701,145,022 - 1,150,858 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005400641 (Get FASTA)   NCBI Sequence Viewer  
  XP_005400642 (Get FASTA)   NCBI Sequence Viewer  
  XP_005400643 (Get FASTA)   NCBI Sequence Viewer  
  XP_013378300 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005400643   ⟸   XM_005400586
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_005400641   ⟸   XM_005400584
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_005400642   ⟸   XM_005400585
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_013378300   ⟸   XM_013522846
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSCLAP00000007094   ⟸   ENSCLAT00000007206
RefSeq Acc Id: ENSCLAP00000007093   ⟸   ENSCLAT00000007205


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000004988 Ensembl, ENTREZGENE
Ensembl Protein ENSCLAP00000007093 ENTREZGENE
Ensembl Transcript ENSCLAT00000007205 ENTREZGENE
NCBI Gene Il1rn ENTREZGENE

 



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.