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Gene: Top1 (DNA topoisomerase I) Chinchilla lanigera
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Symbol: Top1
Name: DNA topoisomerase I
Description: ENCODES a protein that exhibits ATP binding (ortholog); chromatin binding (ortholog); DNA binding (ortholog); INVOLVED IN chromatin remodeling (ortholog); chromosome segregation (ortholog); circadian regulation of gene expression (ortholog); PARTICIPATES IN irinotecan pharmacodynamics pathway; irinotecan pharmacokinetics pathway; ASSOCIATED WITH disease of cellular proliferation (ortholog); Disease Progression (ortholog); Drug-Related Side Effects and Adverse Reactions (ortholog); FOUND IN fibrillar center (ortholog); nuclear chromosome (ortholog); nucleolus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: DNA topoisomerase 1; topoisomerase (DNA) I
Orthologs:
Homo sapiens (human) : TOP1 (DNA topoisomerase I)  HGNC  Alliance
Mus musculus (house mouse) : Top1 (topoisomerase (DNA) I)  MGI  Alliance
Rattus norvegicus (Norway rat) : Top1 (DNA topoisomerase I)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : TOP1 (DNA topoisomerase I)
Canis lupus familiaris (dog) : TOP1 (DNA topoisomerase I)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Top1 (DNA topoisomerase I)
Sus scrofa (pig) : TOP1 (DNA topoisomerase I)
more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495544515,834,017 - 15,922,785 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated

Genomics

Comparative Map Data

Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
 
More on Top1
NCBI Gene
Ensembl Gene
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 8905570
Created: 2014-08-14
Species: Chinchilla lanigera
Last Modified: 2019-01-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.