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Identification of a 35 kDa protein in rat spinal ganglia and sensory fibers.

Authors: Li, Q  Guan, H  Pu, X 
Citation: Li Q, etal., Neuroreport. 2004 Sep 15;15(13):2083-7.
Pubmed: (View Article at PubMed) PMID:15486486

A 35 kDa protein was purified from rat spinal ganglia and sensory fibers. Combined direct trypsin digest and liquid chromatography ion trap mass spectrometry analysis, the 35 kDa protein was identified as annexin V. We then studied the distribution of serum antibodies to annexin V in patients with peripheral neuropathy. We found serum positive antibodies to annexin V only in some patients with immune-mediated neuropathy. This indicated that humoral immune responses to annexin V might play a role in the pathogenesis of autoimmune sensory neuropathy or sensory neuronopathy.


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CRRD Object Information
CRRD ID: 10053691
Created: 2015-07-20
Species: All species
Last Modified: 2015-07-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.