Xenobiotic gene polymorphisms and susceptibility to multiple myeloma.

Authors: Lincz, LF  Kerridge, I  Scorgie, FE  Bailey, M  Enno, A  Spencer, A 
Citation: Lincz LF, etal., Haematologica. 2004 May;89(5):628-9.
Pubmed: (View Article at PubMed) PMID:15136237

Genetic variations in the activity of xenobiotic enzymes may predict susceptibility to multiple myeloma (MM). In a case-control study, 90 Australian Caucasians with MM had significantly higher incidences of GST T1 null, PON1 BB and NAT2 slow acetylation genotypes, but no difference in polymorphism frequencies for GST M1, NAT1, and CYP1A1 when compared to 205 controls.

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CRRD Object Information
CRRD ID: 10450846
Created: 2016-01-22
Species: All species
Last Modified: 2016-01-22
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.