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Identification of blood microRNAs associated to Parkinsonis disease.

Authors: Margis, R  Margis, R  Rieder, CR 
Citation: Margis R, etal., J Biotechnol. 2011 Mar 20;152(3):96-101. doi: 10.1016/j.jbiotec.2011.01.023. Epub 2011 Feb 3.
Pubmed: (View Article at PubMed) PMID:21295623
DOI: Full-text: DOI:10.1016/j.jbiotec.2011.01.023

The present study demonstrates that blood samples can be used as a source of miRNA identification associated to Parkinson's disease (PD). A set of six differentially expressed microRNAs were identified. They form two groups according to their expression profile in control, non-treated, early-onset and treated Parkinson's disease subjects. While miR-1, miR-22* and miR-29 expression levels allowed to distinguish non-treated PD from healthy subjects, miR-16-2*, miR-26a2* and miR30a differentiated treated from untreated patients. This study is innovative in contributing to the development of effective PD biomarkers.


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CRRD Object Information
CRRD ID: 10755488
Created: 2016-01-29
Species: All species
Last Modified: 2016-01-29
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.