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No association between bronchial asthma and HLA-DRB1, -DQB1 alleles in the Slovak population.

Authors: Dzurilla, M  VrlĂ­k, M  Homolová, M  Buc, M 
Citation: Dzurilla M, etal., Bratisl Lek Listy. 2013;114(2):93-5.
Pubmed: (View Article at PubMed) PMID:23331206

109 patients (62 boys/men and 47 girls/women) suffering from bronchial asthma induced by pollen allergens were typed for HLA-DRB1 and -DQBl alleles, respectively, by a low resolution SSP technique. Frequencies of DRB1 alleles varied from 0.5 % to 16.1 %. The most frequent was HLA-DRB1*11 (16.1 %), the least frequent HLA-DRB1*09 (0.4 %). Occurrence rates of HLA-DQB1 alleles ranged from 2.3 % to 37.2 %, HLA-DQB1*03 being the most frequent (37.2 %) and DQB1*04 stood on the opposite pole (2.3 %). By comparing to occurrence rates in the healthy population, no statistically significant differences were disclosed (Tab. 2, Ref. 16).


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CRRD Object Information
CRRD ID: 13506906
Created: 2018-02-22
Species: All species
Last Modified: 2018-02-22
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.