Serum mannose-binding lectin levels are decreased in behcet's disease and associated with disease severity.

Authors: Inanc, N  Mumcu, G  Birtas, E  Elbir, Y  Yavuz, S  Ergun, T  Fresko, I  Direskeneli, H 
Citation: Inanc N, etal., J Rheumatol. 2005 Feb;32(2):287-91.
Pubmed: (View Article at PubMed) PMID:15693089

OBJECTIVE: To investigate serum levels of mannose-binding lectin (MBL), a complement-like protein of collectin family, in patients with Behcet's disease (BD). METHODS: MBL levels were measured in sera of 130 patients with BD, 64 patients with recurrent oral ulcerations (ROU), and 105 healthy controls (HC) with ELISA. RESULTS: Patients with BD had significantly lower median serum MBL levels compared to HC (1857 vs 3136 ng/ml, p = 0.001). No significant difference was observed in median serum MBL levels between BD and ROU (2309 ng/ml, p = 0.252). Low MBL levels (/= 4) was more frequently observed in BD patients with very low serum MBL levels (

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CRRD Object Information
CRRD ID: 1582155
Created: 2006-11-02
Species: All species
Last Modified: 2006-11-02
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.