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Association study of the frizzled-3 (FZD3) gene with schizophrenia and mood disorders.

Authors: Hashimoto, R  Suzuki, T  Iwata, N  Yamanouchi, Y  Kitajima, T  Kosuga, A  Tatsumi, M  Ozaki, N  Kamijima, K  Kunugi, H 
Citation: Hashimoto R, etal., J Neural Transm. 2005 Feb;112(2):303-7.
Pubmed: (View Article at PubMed) PMID:15657645
DOI: Full-text: DOI:10.1007/s00702-004-0264-2

Two research groups have recently reported a significant association between schizophrenia and genetic variants of Frizzled-3 (FZD3) gene. We examined a possible association in a Japanese sample of schizophrenia, bipolar disorder, unipolar depression and controls with four single nucleotide polymorphisms (SNPs), tested in previous reports. We failed to find significant association in the four SNPs or haplotype analysis. The FZD3 gene might not play a role in conferring susceptibility to major psychosis in our sample.

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CRRD Object Information
CRRD ID: 1582651
Created: 2006-11-16
Species: All species
Last Modified: 2006-11-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.