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BMP4 expression in the developing rat retina.

Authors: Maruyama, Y  Mikawa, S  Hotta, Y  Sato, K 
Citation: Maruyama Y, etal., Brain Res. 2006 Nov 29;1122(1):116-21. Epub 2006 Oct 27.
Pubmed: (View Article at PubMed) PMID:17069773
DOI: Full-text: DOI:10.1016/j.brainres.2006.08.130

We investigated the expression of bone morphogenetic protein-4 (BMP4) in the developing retina. At E19, we found very intense BMP4 immunoreactivity (IR) in the nerve fiber layer. At P1, the inner plexiform layer exhibited very strong BMP4-IR. Thereafter, abundant BMP4 expression was kept to the adult period. These results suggest that BMP4 plays pivotal roles in the retina not only in the early embryonic period but also in the late embryonic and postnatal periods, and even in the adult.

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CRRD Object Information
CRRD ID: 2289001
Created: 2008-01-14
Species: All species
Last Modified: 2008-01-14
Status: ACTIVE



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