Growth inhibition of a human oral bacterium Porphyromonas gingivalis by rat cysteine proteinase inhibitor cystatin S.

Authors: Umemoto, T  Naito, Y  Li, M  Suzuki, I  Namikawa, I 
Citation: Umemoto T, etal., Lett Appl Microbiol. 1996 Sep;23(3):151-3.
Pubmed: (View Article at PubMed) PMID:8862019

Agar diffusion analysis demonstrated that rat cystatin S, a cysteine proteinase inhibitor, inhibited the growth of all tested strains of a human oral, Gram-negative anaerobic periodontopathogen Porphyromonas gingivalis. Its specific inhibitory activity against this tissue-invasive bacterium but not against other tested oral bacterial species emphasized the importance of specific cysteine proteinases for growth of P. gingivalis.


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CRRD Object Information
CRRD ID: 2306756
Created: 2009-05-05
Species: All species
Last Modified: 2009-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.