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Molecular cloning and expression of rat betacellulin cDNA.

Authors: Tada, H  Seno, M  Yamada, H  Sasada, R  Igarashi, K 
Citation: Tada H, etal., Biochim Biophys Acta 2000 Jun 21;1492(1):285-8.
Pubmed: (View Article at PubMed) PMID:11004502

The cDNA encoding an entire open reading frame of rat betacellulin has been cloned from rat kidney. Expression of this cDNA in COS7 cells showed a significant amount of mitogenic activity in the culture media. Western blotting of the cell lysates suggested that the membrane-anchored precursor was cleaved to release its ectodomain very efficiently.


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CRRD Object Information
CRRD ID: 631927
Created: 2003-08-21
Species: All species
Last Modified: 2004-05-25
Status: ACTIVE


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