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A linkage map of the rat genome derived from three F2 crosses.

Authors: Bihoreau, MT  Gauguier, D  Kato, N  Hyne, G  Lindpaintner, K  Rapp, JP  James, MR  Lathrop, GM 
Citation: Bihoreau MT, etal., Genome Res 1997 May;7(5):434-40.
Pubmed: (View Article at PubMed) PMID:9149940

We report the construction of a dense linkage map of the rat genome integrating 767 simple sequence length polymorphism markers, combined over three crosses with high rates of polymorphism. F2 populations from WKY x S (n = 159), BN x S (n = 91), and BN x GK (n = 139) were selected and genotyped for combinations of microsatellite markers. The loci define 21 linkage groups corresponding to the 20 rat autosomal chromosomes and the X chromosome. The map spans a genetic length of 1998 cM. This combined linkage map should facilitate the advancement of genetic studies for a wide variety of rat models characterized for complex phenotypes.


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CRRD Object Information
CRRD ID: 70318
Created: 2002-03-13
Species: All species
Last Modified: 2002-03-13
Status: ACTIVE


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