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Development dependent collagen gene expression in the rat cranial base growth plate.

Authors: Romer, P  Weingartner, J  Roldan, JC  Proff, P  Reicheneder, C 
Citation: Romer P, etal., Ann Anat. 2010 Aug 20;192(4):205-9. doi: 10.1016/j.aanat.2010.05.006. Epub 2010 Jun 11.
Pubmed: (View Article at PubMed) PMID:20591638
DOI: Full-text: DOI:10.1016/j.aanat.2010.05.006

The spheno-occipital synchondrosis is part of the cranial base growth plate and is of crucial importance in craniofacial development. In this investigation, we studied changes in collagen gene expression in the spheno-occipital synchondrosis in order to identify the developmental stages most important for extracellular matrix production and ossification of the rat cranial base growth plate. Gene transcripts of type II and X collagen were most abundant at day 10 postnatally in the spheno-occipital synchondrosis. This observation is assumed to be due to intrinsic genetic factors and local environmental factors.


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CRRD Object Information
CRRD ID: 8661256
Created: 2014-06-10
Species: All species
Last Modified: 2014-06-10
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.