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Strain: DA.PVG.1AV1-(D10Got406-D10Rat93)/Kini

Symbol: DA.PVG.1AV1-(D10Got406-D10Rat93)/Kini
Strain: DA.PVG.1AV1-(D10Got406-D10Rat93)
Substrain: Kini
Ontology ID: RS:0003746
Also known as: DA.PVG.1AV1-(D10Got406-D10Rat93)/Kini; DA.PVG.1AV1-Eae18b; NBRP Rat No: 0698
Type: congenic
Source: Center for Molecular Medicine, Neuroimmunology Unit, Karolinska Institutet, Stockholm, Sweden, National BioResource Project for the Rat in Japan
Origin: Inbred Dark Agouti (DA) rats were originally obtained from Hannover, Germany and Piebald Virol Glaxo(PVG) rats from Harlan UK Limited (Blackthorn, UK). Animals for congenic breeding were selected from the 10th generation of an advanced intercross line (AIL) originating from the EAE-susceptible DA and EAE-resistant PVG.1AV1 rat strains. Selected males containing a PVG.1AV1 fragment in the Eae18b region (from OT24.18 to D10Rat93 marker, at 68.36 Mb and 81.9 Mb, respectively) were backcrossed with DA females for 8 generations, and offspring was genotyped using microsatellite markers in each generation. In the 8th generation, heterozygous males and females were crossed to obtain the experimental population of homozygous congenic rats and littermate controls.
Coat Color: agouti
Last Known Status: Cryopreserved Sperm
Research Usage Neurobiology
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01067,495,867 - 80,946,110RGD_MAPPER_PIPELINERnor6.0
Rnor_5.01067,154,600 - 80,788,180RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.41068,361,384 - 81,887,390RGD_MAPPER_PIPELINERGSC3.4

Experimental Data Annotations
References - curated


Position Markers

Additional Information

RGD Curation Notes
Nomenclature History
More on this Strain
Strain Nomenclature
Strain Registration

CRRD Object Information
CRRD ID: 8552337
Created: 2014-04-21
Species: Rattus norvegicus
Last Modified: 2014-04-21
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.